Shows Like 12 oz. Mouse

If you liked 12 oz. Mouse (2005), a animation and comedy series, here are 20 shows with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

1
Ten Year Old Tom (2021)
★ 6.9/10Also animation and comedy
The misadventures of an average kid as he contends with questionable guidance from the well-meaning grownups around him.
2
Aqua Teen Hunger Force (2000)
★ 7.5/10Also animation and comedy
The surreal adventures of three anthropomorphic fast food items: Master Shake, Frylock and Meatwad, and their human nextdoor neighbor, Carl Brutananadilewski.
3
Grimsburg (2024)
★ 6.1/10Also animation and comedy
Marvin Flute may be the greatest detective ever to catch a cannibal clown or correctly identify a mid-century modern armoire. But there’s one mystery he still can’t crack — his family. Now that he's back in Grimsburg…
4
Squidbillies (2005)
★ 6.9/10Also comedy and animation
Squidbillies is an animated television series about the Cuylers, an impoverished family of anthropomorphic hillbilly mud squids living in the Appalachian region of Georgia's mountains. The show is produced by Williams…
5
Robot Chicken (2005)
★ 7.6/10Also comedy and animation
A series of pop-culture parodies using stop-motion animation of toys, action figures and dolls. The title character was an ordinary chicken until he was run down by a car and subsequently brought back to life in cyborg…
6
Seth MacFarlane's Cavalcade of Cartoon Comedy (2008)
★ 5.9/10Also animation and comedy
Seth MacFarlane's Cavalcade of Cartoon Comedy is an American cartoon web series created by Seth MacFarlane. The series is based on the cutaway jokes on Family Guy.
7
Clerks (2000)
★ 7.2/10Also animation and comedy
The continuing adventures of store clerks Dante and Randal, who try to make the best of their menial labor, with no help from Jay and Silent Bob.
8
Ugly Americans (2010)
★ 8.2/10Also animation and comedy
Social worker Mark Lilly helps new citizens—both human and "other"—begin the process of adapting to life in the Big Apple, but his coworkers, demonic bureaucrat Twayne, drunken wizard Leonard Powers, surly law…
9
The Life & Times of Tim (2008)
★ 7.3/10Also animation and comedy
This show is about a hapless man in his mid-20's named Tim who lives in New York City with his girlfriend Amy. Throughout the series, Tim constantly finds himself in increasingly awkward situations in both his work and…
10
Code Monkeys (2007)
★ 7.2/10Also animation and comedy
Set in the early 1980s, Code Monkeys follows the adventures of fictional video game company GameAVision.
11
Koala Man (2023)
★ 6.6/10Also animation and comedy
A powerless superhero and family patriarch in an Australian suburb lives a not-so-secret identity as Koala Man while possessing a burning passion to snuff out petty crime and bring order the community.
12
China, IL (2011)
★ 6.8/10Also animation and comedy
The absurdist legacy of the worst college in America is set to unfold, as the Professor Brothers, Steve and Frank Smith, alongside their colleagues, deal with life, each other, and the nagging responsibility of their…
13
Solar Opposites (2020)
★ 7.8/10Also comedy and animation
A family of aliens from a much better world must take refuge in middle America after the destruction of their planet. Their mission: protect the Pupa, a living super computer that will one day evolve into its true…
14
Unsupervised (2012)
★ 6.6/10Also animation and comedy
15-year-old best friends Gary and Joel try to navigate teenage life while also trying to do the right thing without the help of any parental supervision.
15
Happy Tree Friends (2000)
★ 7.8/10Also animation and comedy
This action and adventure comedy is drawn in simple appearance and combines cute forest animals with extreme graphic violence. Each episode revolves around the characters enduring accidental events of bloodshed, pain…
16
Long Story Short (2025)
★ 7.5/10Also comedy and animation
From the creator of "BoJack Horseman" comes this animated comedy about a family over time, following siblings from childhood to adulthood and back again.
17
Rooster Fighter (2026)
★ 8.8/10Also animation and comedy
Keiji is more than just an ordinary rooster—he's humanity's greatest defender! His opponents may be ten stories tall, but nothing is bigger than his stout heart and his fearsome battle cry—Kokekokko!
18
Ricky Gervais Alley Cats (2026)
★ 7.8/10Also animation and comedy
Outrageous misadventures run wild as feral cats cause chaos on the streets in this no-holds-barred animated comedy from Ricky Gervais.
19
Marvel's M.O.D.O.K. (2021)
★ 6.7/10Also comedy and animation
The megalomaniacal supervillain M.O.D.O.K. has long pursued his dream of one day conquering the world. But after years of setbacks and failures fighting the Earth’s mightiest heroes, M.O.D.O.K. has run his evil…
20
The Shivering Truth (2018)
★ 7.4/10Also comedy and animation
A miniature propulsive omnibus clusterbomb of painfully riotous daymares all dripping with the orange goo of dream logic. A series of loosely linked emotional parables about stories within tales that crawled out of the…