Movies Like The Strange Case of Doctor Rx
If you liked The Strange Case of Doctor Rx (1942), a horror and mystery movie directed by William Nigh, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.
- 1

Tightrope (1984)
★ 6.2/10Also mysteryWes Block is a detective who's put on the case of a serial killer whose victims are young and pretty women. The murders are getting personal when the killer chooses victims who are acquaintances of Block. Even his…
- 2

The Mirror Crack'd (1980)
★ 6.1/10Also mysteryJane Marple solves the mystery when a local woman is poisoned and a visiting movie star seems to have been the intended victim.
- 3

Cult Killer (2024)
★ 6.4/10Also mystery and horrorA private investigator is forced into a dangerous alliance with a killer in order to uncover a quiet town’s grisly criminal underbelly and clear the name of her mentor, who is implicated in the crimes.
- 4

Crooked House (2017)
★ 6.4/10Also mysteryA private investigator helps a former flame solve the murder of her wealthy grandfather, who lived in a sprawling estate surrounded by his idiosyncratic family.
- 5

I See You (2019)
★ 7/10Also horror and mysteryWhen a 12-year-old boy goes missing at a local park, a detective investigates the case to help the boy's family find answers.
- 6

Strange Harvest (2025)
★ 6.6/10Also horror and mysteryDetectives are thrust into a chilling hunt for a sadistic serial killer from the past whose return marks the beginning of a new wave of grotesque, otherworldly crimes tied to a cosmic force.
- 7

Lady in the Lake (1946)
★ 6.1/10Also mysteryPrivate eye Phillip Marlowe wants to get out of the detective racket and into crime writing. But when he's called to the office of editor Adrienne Fromsett, it's not to talk about his story ideas — she wants him to…
- 8

Striking Distance (1993)
★ 5.9/10Also mysteryDemoted Pittsburgh cop Tom Hardy works river patrol while a serial killer targets women from his past, forcing him to conduct an unauthorized investigation to prove his innocence and expose a dirty cop.
- 9

The Maltese Falcon (1941)
★ 7.7/10Also mysteryA private detective takes on a case that involves him with three eccentric criminals, a beautiful liar, and their quest for a priceless statuette.
- 10

The Big Sleep (1946)
★ 7.6/10Also mysteryPrivate Investigator Philip Marlowe is hired by wealthy General Sternwood regarding a matter involving his youngest daughter Carmen. Before the complex case is over, Marlowe sees murder, blackmail, deception, and what…
- 11

Cleaner (2007)
★ 6.1/10Also mysterySingle father and former cop Tom Cutler has an unusual occupation: he cleans up death scenes. But when he's called in to sterilize a wealthy suburban residence after a brutal shooting, Cutler is shocked to learn he may…
- 12

Body Cam (2020)
★ 6.2/10Also horror and mysteryAs a police officer investigates the gruesome murder of her colleague, she discovers that a mysterious supernatural force is behind it.
- 13

Muzzle: City of Wolves (2025)
★ 6.6/10Also mysteryLAPD officer Jake Rosser endeavors to lead a peaceful life with his family and retired K-9 officer, Socks. However, tranquility dissolves into chaos when a gang targets them in a brutal attack. Alongside his new K-9…
- 14

The Seven-Ups (1973)
★ 6.3/10Also mysteryA tough detective who is part of an elite New York City unit is trying to find out who killed his partner, but uncovers a plot to kidnap mobsters for money.
- 15

Woman on the Run (1950)
★ 6.8/10Also mysteryFrank Johnson, a sole witness to a gangland murder, goes into hiding and is trailed by Police Inspector Ferris, on the theory that Frank is trying to escape from possible retaliation. Frank's wife, Eleanor, suspects he…
- 16

The Adventures of Sherlock Holmes (1939)
★ 6.9/10Also mysteryHaving once again avoided criminal conviction, Professor Moriarity develops a murderous plan to “finish off” his last major nemesis, Sherlock Holmes, by making him fail to prevent the perfect crime. Does it involve a…
- 17

Shadow of a Doubt (1943)
★ 7.5/10Also mysteryIn sleepy Santa Rosa, restless young Charlie’s world brightens when her sophisticated Uncle Charlie arrives for a long visit. But as his behavior grows increasingly strange, she begins to suspect that her beloved uncle…
- 18

Psycho Killer (2026)
★ 6.7/10Also horror and mysteryFollowing the brutal murder of her husband, a Kansas highway patrol officer sets out on a journey to track down the perpetrator. As the hunt progresses, she comes to realize the man responsible is a sadistic serial…
- 19

God Told Me To (1976)
★ 5.9/10Also horror and mysteryA New York detective investigates a series of murders committed by random citizens who claim that 'God told them to'.
- 20

Blue Velvet (1986)
★ 7.6/10Also mysteryThe discovery of a severed human ear found in a field leads a young man on an investigation related to a beautiful, mysterious nightclub singer and a group of psychopathic criminals who have kidnapped her child.