Movies Like Weird Science 2: Strange Chemistry

If you liked Weird Science 2: Strange Chemistry (2013), a comedy and science fiction movie directed by Charles Ingram, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

1
Relax, I'm from the Future (2023)
★ 5.9/10Also comedy and science fiction
Casper is a time traveller who arrives in the 2020s in an attempt to prevent a major future catastrophe. He meets Holly, a queer black woman he befriends and draws into his plan by giving her his knowledge of the…
2
Real Men (1987)
★ 6/10Also comedy and science fiction
A womanizing CIA agent and an insecure insurance agent are paired together to make sure a deal goes through with aliens for the future of mankind.
3
Afterburn (2025)
★ 6.2/10Also science fiction and comedy
Set against the backdrop of a postapocalyptic Earth whose Eastern Hemisphere was destroyed by a massive solar flare, leaving what life remains mutated from radiation and fallout. The story revolves around a group of…
4
Sleeper (1973)
★ 6.8/10Also comedy and science fiction
Miles Monroe, a clarinet-playing health food store proprietor, is revived out of cryostasis 200 years into a future world in order to help rebels fight an oppressive government regime.
5
Dark Star (1974)
★ 6/10Also comedy and science fiction
A group of scientists are sent on a mission to destroy unstable planets. Twenty years into their mission, they have to battle their alien mascot as well as a "sensitive" and intelligent bombing device that starts to…
6
The Bed Sitting Room (1969)
★ 5.9/10Also comedy and science fiction
In the hazy aftermath of World War III, the fallout from a 'nuclear misunderstanding' is producing strange mutations amongst the survivors, and the noble Lord Fortnum finds himself transforming into a bed sitting room.
7
Amazon Women on the Moon (1987)
★ 5.9/10Also comedy and science fiction
Centered on a television station which features a 1950s-style sci-fi movie interspersed with a series of wild commercials, wacky shorts and weird specials, this lampoon of contemporary life and pop culture skewers some…
8
The Man in the White Suit (1951)
★ 6.9/10Also comedy and science fiction
The unassuming, nebbishy inventor Sidney Stratton creates a miraculous fabric that will never be dirty or worn out. Clearly he can make a fortune selling clothes made of the material, but may cause a crisis in the…
9
Monkey Business (1952)
★ 6.7/10Also comedy and science fiction
Research chemist Barnaby Fulton works on a fountain of youth pill for a chemical company. One of the labs chimps gets loose in the laboratory and mixes chemicals, but then pours the mix into the water cooler. When…
10
South Park: Joining the Panderverse (2023)
★ 7.5/10Also comedy and science fiction
Cartman's deeply disturbing dreams portend the end of the life he knows and loves. Meanwhile, the adults in South Park are wrestling with their own life decisions, as the advent of AI is turning their world upside down.
11
Team Thor: Part 2 (2017)
★ 6.9/10Also science fiction and comedy
A continuation of the documentary spoof of what Thor and his roommate Darryl were up to during the events of "Captain America: Civil War". While Cap and Iron Man duke it out, Thor tries to pay Darryl his rent in…
12
Yellow Mirror (2026)
★ 8.1/10Also comedy and science fiction
A defective lamp reveals a heartbreaking truth about what Homer believes is reality, and an AI-powered tablet befriends and controls Maggie. The Simpsons struggle to find the light through two dark tales of the curious…
13
Stewie Griffin: The Untold Story (2005)
★ 6.9/10Also comedy and science fiction
The maniacal baby of the Griffin family, Stewie, meets his future self. In doing this he discovers that his future image is not what he has anticipated because of a near death experience.
14
Team Thor (2016)
★ 7.2/10Also comedy and science fiction
Discover what Thor was up to during the events of Captain America: Civil War.
15
Family Guy Presents: Blue Harvest (2007)
★ 7.4/10Also comedy and science fiction
With the Griffins stuck at home during a blackout, Peter tells the story of "Star Wars Episode IV: A New Hope".
16
Repo Man (1984)
★ 6.6/10Also comedy and science fiction
A down and out young punk gets a job working with a seasoned repo man, but what awaits him in his new career is a series of outlandish adventures revolving around aliens, the CIA, and a most wanted '64 Chevy.
17
Plankton: The Movie (2025)
★ 6.6/10Also comedy and science fiction
Plankton's tangled love story with his sentient computer wife goes sideways when she takes a stand — and decides to destroy the world without him.
18
Groot's First Steps (2022)
★ 7/10Also comedy and science fiction
Following the events of “Guardians of the Galaxy Vol. 1,” Baby Groot is finally ready to try taking his first steps out of his pot—only to learn you have to walk before you can run.
19
Unidentified Flying Mater (2009)
★ 6.3/10Also science fiction and comedy
Mater finds a small UFO called Mator and they have a night out. Later, when Mator is captured by military forces, Mater sneaks up and saves him with the help of Lightning McQueen and the UFO's mother.
20
Robot Chicken: Star Wars Episode II (2008)
★ 7.5/10Also science fiction and comedy
Seth Green and Matthew Senreich serve up more hilarious Star Wars-inspired satire in this second compilation of sketches featuring the zany stop-motion animation of Adult Swim's "Robot Chicken." Gary the stormtrooper…