Movies Like Dr. Moreau's House of Pain

If you liked Dr. Moreau's House of Pain (2004), a horror and science fiction movie directed by Charles Band, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

1
Books of Blood (2020)
★ 6.2/10Also horror and science fiction
A journey into uncharted and forbidden territory through three tales tangled in space and time.
2
Dark Light (2019)
★ 6.2/10Also horror and science fiction
A woman returns to her family home and discovers it to be inhabited by monsters.
3
Blood and Snow (2023)
★ 6.2/10Also science fiction and horror
When researchers rescue a fellow scientist who survived a meteorite strike in the Arctic, they discover she may not be who they think she is. Is she some-how changed?
4
The Resurrected (1991)
★ 6.2/10Also horror and science fiction
Charles Dexter Ward, a wealthy scientist, uses an ancient diary and human remains to begin a terrifying and bloody pursuit for immortality.
5
The Kindred (1987)
★ 6/10Also horror and science fiction
Amanda's deathbed request to her son, John, was for him to destroy all the lab notes etc. from her last experiment. She also blurts out he had a brother. At the funeral John meets Melissa, who claims to be his mother's…
6
Daylight's End (2016)
★ 5.8/10Also horror and science fiction
Years after a mysterious plague has devastated the planet and turned most of humanity into blood-hungry creatures, a rogue drifter on a vengeful hunt stumbles across a band of survivors in an abandoned police station…
7
Hollow Man (2000)
★ 6/10Also science fiction
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the…
8
Goodnight Mommy (2022)
★ 6.3/10Also horror
When twin brothers arrive home to find their mother’s demeanor altered and face covered in surgical bandages, they begin to suspect the woman beneath the gauze might not be their mother.
9
Southbound (2015)
★ 5.9/10Also horror and science fiction
On a desolate stretch of desert highway, weary travelers — two men on the run from their past, a band on their way to the next gig, a man struggling to get home, a brother in search of his long-lost sister and a family…
10
Cheat (2023)
★ 7.1/10Also horror
On the surface it's believed to be another urban legend - a supernatural being from the afterlife is violently killing anyone who cheats on their significant other in the small college town of Silvercreek…
11
Death Machine (1995)
★ 5.8/10Also horror and science fiction
Chaank Armaments is experimenting with the ultimate fighting machine which is part human - part machine. So far, the Hardman project has been unreliable and has killed a number of innocent people. The genius behind…
12
God Is a Bullet (2023)
★ 6.3/10Also horror
Vice detective Bob Hightower finds his ex-wife murdered and daughter kidnapped by a cult. Frustrated by the botched official investigations, he quits the force and infiltrates the cult to hunt down the leader with the…
13
The Banana Splits Movie (2019)
★ 6.5/10Also horror
A boy named Harley and his family attend a taping of The Banana Splits TV show, which is supposed to be a fun-filled birthday for young Harley and business as usual for Rebecca, the producer of the series. But things…
14
Infinity Pool (2023)
★ 6/10Also horror and science fiction
While staying at an isolated island resort, James and Em are enjoying a perfect vacation of pristine beaches, exceptional staff, and soaking up the sun. But guided by the seductive and mysterious Gabi, they venture…
15
Strange Darling (2024)
★ 6.9/10Also horror
Nothing is what it seems when a twisted one-night stand spirals into a serial killer’s vicious murder spree.
16
Bone Lake (2025)
★ 5.9/10Also horror
A couple’s romantic vacation at a secluded lakeside estate is upended when they are forced to share the mansion with a mysterious and attractive couple. In this darkly hilarious and seductive horror story, a dream…
17
Replicant (2001)
★ 5.9/10Also science fiction
Scientists create a genetic clone of a serial killer in order to help catch the killer, teaming up with two cops.
18
Frankenstein Must Be Destroyed (1969)
★ 6.3/10Also horror and science fiction
Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant…
19
The Cell (2000)
★ 6.3/10Also horror and science fiction
A psychotherapist journeys inside the mind of a comatose serial killer in the hopes of saving his latest victim.
20
The Divide (2012)
★ 5.9/10Also horror and science fiction
Survivors of a nuclear attack are grouped together for days in the basement of their apartment building, where fear and dwindling supplies wear away at their dynamic.