Movies Like Dr. Jekyll & Mistress Hyde

If you liked Dr. Jekyll & Mistress Hyde (2003), a science fiction and drama movie directed by Tony Marsiglia, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

1
Dr. Jekyll and Mr. Hyde (1920)
★ 6.7/10Also horror and science fiction
A doctor's research into the roots of evil turns him into a hideous depraved fiend.
2
Vesper (2022)
★ 6.2/10Also science fiction and drama
After the collapse of Earth's ecosystem, Vesper, a 13-year-old girl struggling to survive with her paralyzed Father, meets a mysterious Woman with a secret that forces Vesper to use her wits, strength and bio-hacking…
3
The Brood (1979)
★ 6.7/10Also horror and science fiction
A man tries to uncover an unconventional psychologist's therapy techniques on his institutionalised wife, amidst a series of brutal murders.
4
The Zero Theorem (2013)
★ 6.1/10Also drama and science fiction
A computer hacker's goal to discover the reason for human existence continually finds his work interrupted thanks to the Management; this time, they send a teenager and lusty love interest to distract him.
5
Blood and Snow (2023)
★ 6.2/10Also science fiction and horror
When researchers rescue a fellow scientist who survived a meteorite strike in the Arctic, they discover she may not be who they think she is. Is she some-how changed?
6
From Beyond (1986)
★ 6.5/10Also horror and science fiction
The Resonator, a powerful machine that can control the sixth sense, has killed its creator and sent his associate into an insane asylum. When a psychiatrist becomes determined to continue the experiment, she…
7
Scanners (1981)
★ 6.7/10Also science fiction and horror
A scientist trains a man with an advanced telepathic ability called 'scanning' to stop a dangerous Scanner with extraordinary psychic powers from waging war against non-Scanners.
8
2073 (2024)
★ 6.7/10Also science fiction and drama
Inspired by Chris Marker's iconic 1962 featurette La Jetée; the year is 2073—a not-so-distant dystopian future—and the setting is New San Francisco, the scorched-earth tech-dominant police state where democracy and…
9
Containment (2015)
★ 5.9/10Also horror and science fiction
Neighbors in a block wake one morning to find they have been sealed inside their apartments. Can they work together to find out why? Or will they destroy each other in their fight to escape?
10
The Asphyx (1972)
★ 6/10Also horror and science fiction
Hugo is a brilliant turn-of-the-century scientist, loved and respected by his family and friends, admired by his colleagues. But he is a man quickly becoming obsessed with a curious and frightening question...What is…
11
Die Alone (2024)
★ 6.5/10Also horror and science fiction
Lost in a world reclaimed by nature and overrun by mysterious creatures, Ethan, a young man with amnesia navigates the dangerous landscape in search of his lost love Emma. His journey takes an unexpected turn when he…
12
Don't Worry Darling (2022)
★ 6.8/10Also science fiction and horror
Alice and Jack are lucky to be living in the idealized community of Victory, the experimental company town housing the men who work for the top-secret Victory Project and their families. But when cracks in their…
13
The Thing (2011)
★ 6.3/10Also horror and science fiction
When paleontologist Kate Lloyd travels to an isolated outpost in Antarctica for the expedition of a lifetime, she joins an international team that unearths a remarkable discovery. Their elation quickly turns to fear as…
14
Crimes of the Future (2022)
★ 6/10Also science fiction and horror
With his partner Caprice, celebrity performance artist Saul Tenser publicly showcases the metamorphosis of his organs in avant-garde performances. An investigator from the National Organ Registry obsessively tracks…
15
Species (1995)
★ 6/10Also science fiction and horror
In 1993, the Search for Extra Terrestrial Intelligence Project receives a transmission detailing an alien DNA structure, along with instructions on how to splice it with human DNA. The result is Sil, a sensual but…
16
Altered States (1980)
★ 6.7/10Also horror and science fiction
A research scientist explores the boundaries and frontiers of human consciousness. Using sensory deprivation and hallucinogenic mixtures from Native American shamans, he explores these altered states of cognizance and…
17
Eraserhead (1977)
★ 7.3/10Also horror and science fiction
First-time father Henry Spencer tries to survive his industrial environment, his angry girlfriend, and the unbearable screams of his newly born mutant child.
18
Frankenstein (2025)
★ 7.6/10Also drama and horror
Dr. Victor Frankenstein, a brilliant but egotistical scientist, brings a creature to life in a monstrous experiment that ultimately leads to the undoing of both the creator and his tragic creation.
19
The Hidden (1987)
★ 6.9/10Also science fiction and horror
When average, law-abiding citizens suddenly turn to a life of hedonistic behavior and violent crime, Detective Tom Beck is tasked with helping young FBI agent Lloyd Gallagher determine the cause.
20
Tau (2018)
★ 6.1/10Also science fiction and horror
Held captive in a futuristic smart house, a woman hopes to escape by befriending the A.I. program that controls the house.