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Movies Like Man with the Screaming Brain

If you liked Man with the Screaming Brain (2005), a comedy and horror movie directed by Bruce Campbell, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

  1. 1The Dead Zone

    The Dead Zone (1983)

    ★ 7/10Also horror and science fiction

    Johnny Smith is a schoolteacher with his whole life ahead of him but, after leaving his fiancee's home one night, is involved in a car crash which leaves him in a coma for 5 years. When he wakes, he discovers he has an…

  2. 2Infestation

    Infestation (2009)

    ★ 5.8/10Also comedy and horror

    After being stung by a giant insect, Cooper learns that these bugs are attacking the whole city. He joins forces with the survivors, in order to find a way to counter-attack.

  3. 3Clayface

    Clayface (2026)

    ★ 7.4/10Also horror and science fiction

    Matt Hagen's meteoric rise from Gotham street kid to Hollywood leading man is tragically cut short when a local crime boss's actions leave him horribly disfigured. Abandoned by his team and with nothing left, Matt…

  4. 4Real Men

    Real Men (1987)

    ★ 6/10Also comedy and science fiction

    A womanizing CIA agent and an insecure insurance agent are paired together to make sure a deal goes through with aliens for the future of mankind.

  5. 5Relax, I'm from the Future

    Relax, I'm from the Future (2023)

    ★ 5.9/10Also comedy and science fiction

    Casper is a time traveller who arrives in the 2020s in an attempt to prevent a major future catastrophe. He meets Holly, a queer black woman he befriends and draws into his plan by giving her his knowledge of the…

  6. 6Re-Animator

    Re-Animator (1985)

    ★ 7.1/10Also science fiction and comedy

    Conducting clandestine experiments within the morgue at Miskatonic University, scientist Herbert West reveals to a fellow graduate student his groundbreaking work concerning the re-animation of fresh corpses.

  7. 7Cold Storage

    Cold Storage (2026)

    ★ 6.7/10Also horror and science fiction

    When a mutating, highly contagious fungus escapes a sealed facility, two employees – joined by a grizzled bioterror operative – must survive the wildest night shift ever to save humanity from extinction.

  8. 8Osiris

    Osiris (2025)

    ★ 6.2/10Also science fiction and horror

    Special Forces commandos on a mission are abducted mid-operation by a mysterious spacecraft. Upon waking aboard, they find themselves prey to a relentless alien race in a fight for survival.

  9. 9Frankenhooker

    Frankenhooker (1990)

    ★ 6.3/10Also comedy and horror

    A medical school dropout loses his fiancée in a tragic lawnmower incident and decides to bring her back to life. Unfortunately, he was only able to save her head, so he goes to the red light district in the city and…

  10. 10The Girl with All the Gifts

    The Girl with All the Gifts (2016)

    ★ 6.6/10Also horror and science fiction

    In the future, a strange fungus has changed nearly everyone into thoughtless, flesh-eating monsters. When a scientist and a teacher find a girl who seems to be immune to the fungus, they all begin a journey to save…

  11. 11Asylum: Twisted Horror and Fantasy Tales

    Asylum: Twisted Horror and Fantasy Tales (2020)

    ★ 5.9/10Also comedy and horror

    Brandon prepares to give his last stand-up comedy show. As his stories and jokes pass, the public begins to cheer up. But at that precise moment Brandon will realize that these stories have a strong relationship with…

  12. 12Good Luck, Have Fun, Don't Die

    Good Luck, Have Fun, Don't Die (2026)

    ★ 7.1/10Also science fiction and comedy

    A 'Man from the Future' arrives at an LA diner where he must recruit the precise combination of disgruntled patrons to join him on a one-night quest to save the world from the terminal threat of a rogue artificial…

  13. 13Die Alone

    Die Alone (2024)

    ★ 6.5/10Also horror and science fiction

    Lost in a world reclaimed by nature and overrun by mysterious creatures, Ethan, a young man with amnesia navigates the dangerous landscape in search of his lost love Emma. His journey takes an unexpected turn when he…

  14. 14The Hidden

    The Hidden (1987)

    ★ 6.9/10Also science fiction and horror

    When average, law-abiding citizens suddenly turn to a life of hedonistic behavior and violent crime, Detective Tom Beck is tasked with helping young FBI agent Lloyd Gallagher determine the cause.

  15. 15Extinction

    Extinction (2015)

    ★ 6.4/10Also horror and science fiction

    And suddenly, overnight, the world came to a halt. Two men, two survivors, one kid, and hatred that separates them. A place forgotten by everyone, including the creatures that inhabit the Earth... until now.

  16. 16Bad Taste

    Bad Taste (1987)

    ★ 6.3/10Also comedy and horror

    A team from the intergalactic fast food chain Crumb's Crunchy Delights descends on Earth, planning to make human flesh the newest taste sensation. After they wipe out the New Zealand town Kaihoro, the country’s…

  17. 17Bride of Re-Animator

    Bride of Re-Animator (1990)

    ★ 6.5/10Also horror and comedy

    Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of…

  18. 18Vampire's Kiss

    Vampire's Kiss (1989)

    ★ 6/10Also comedy and horror

    A publishing executive is visited and bitten by a vampire and starts exhibiting erratic behavior. He pushes his secretary to extremes as he tries to come to terms with his affliction.

  19. 19Long Distance

    Long Distance (2024)

    ★ 6.6/10Also science fiction and comedy

    After crash-landing on an alien planet, an asteroid miner must contend with the challenges of his new surroundings, while making his way across the harsh terrain to the only other survivor – a woman who is trapped in…

  20. 20Prometheus

    Prometheus (2012)

    ★ 6.6/10Also science fiction and horror

    A team of explorers discover a clue to the origins of mankind on Earth, leading them on a journey to the darkest corners of the universe. There, they must fight a terrifying battle to save the future of the human race.

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