Movies Like My Best Friend Depression

If you liked My Best Friend Depression, a movie directed by Heather Le Roy, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

1
Love & Other Drugs (2010)
★ 7/10
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat…
2
Better Living Through Chemistry (2014)
★ 5.9/10
A straight-laced pharmacist's uneventful life spirals out of control when he starts an affair with a trophy wife customer who takes him on a joyride involving sex, drugs and possibly murder.
3
Meet Me Next Christmas (2024)
★ 6.3/10
On a quest to reconnect with the man of her dreams, Layla races across New York City to find a ticket to a sold-out Pentatonix Christmas Eve concert.
4
Valley Girl (1983)
★ 6/10
Julie, a girl from the valley, meets Randy, a punk from the city. They are from different worlds and find love. Somehow they need to stay together in spite of her trendy, shallow friends.
5
Bros (2022)
★ 6.6/10
Two gay men are possibly, probably, stumbling towards love. Maybe. They're both very busy.
6
One Night Only (2026)
★ 6.4/10
Two love-starved strangers crash into each other on the one night of the year when single people are allowed to have sex.
7
Playing It Cool (2014)
★ 5.9/10
A young man meets and instantly falls in love with an engaged woman.
8
F Valentine's Day (2026)
★ 6.1/10
Gina hates her Valentine's Day birthday and travels to Greece to prevent her boyfriend's proposal. With help from vacationers Johnny and his sister Mickey, she schemes to delay it – while questioning her relationship.
9
Love Potion No. 9 (1992)
★ 6.2/10
Unlucky in love, chemist Paul Matthews visits gypsy Madame Rosa for help. Quickly realizing he is a hopeless nerd, she gifts him with Love Potion No. 8, which makes anyone who wears it irresistible to the opposite sex…
10
Love in Taipei (2023)
★ 6.8/10
A young American woman is sent by her parents to a cultural immersion program in Taipei where she begins a new journey of self-discovery and romance.
11
The Apartment (1960)
★ 8.2/10
Bud Baxter is a minor clerk in a huge New York insurance company, until he discovers a quick way to climb the corporate ladder. He lends out his apartment to the executives as a place to take their mistresses. Although…
12
The Wedding Banquet (2025)
★ 6.6/10
Frustrated with his commitment-phobic boyfriend Chris and running out of time, Min makes a proposal: a green-card marriage with their friend Angela in exchange for her partner Lee's expensive IVF. Elopement plans are…
13
This Little Love of Mine (2021)
★ 6.1/10
Laura Price is a successful San Francisco lawyer on the cusp of promotion – a far cry from her childhood growing up on a tropical island with best friends Chip and Gem. When the firm’s biggest client – Chip’s…
14
Easy Virtue (2008)
★ 6.5/10
A young Englishman marries a glamorous American. When he brings her home to meet the parents, she arrives like a blast from the future - blowing their entrenched British stuffiness out the window.
15
Barefoot (2014)
★ 6.7/10
The "black sheep" son of a wealthy family meets a young psychiatric patient who's been raised in isolation her entire life. He takes the naive young woman home for his brother's wedding an improbable romance blooms, as…
16
London (2005)
★ 6/10
London is a drug laden adventure that centers on a party in a New York loft where a young man is trying to win back his ex-girlfriend.
17
Someone Great (2019)
★ 6.4/10
An aspiring music journalist lands her dream job and is about to move to San Francisco when her boyfriend of nine years decides to call it quits. To nurse her broken heart, she and her two best friends spend one…
18
Speechless (1994)
★ 6/10
In the midst of election season in New Mexico, political speechwriters Julia Mann and Kevin Vallick begin a romance, unaware they are working for candidates on opposite sides.
19
Hot Frosty (2024)
★ 5.9/10
When a young widow's magic scarf brings a dashing snowman to life, can he help her rediscover romance, laughter and holiday cheer before he melts away?
20
Someone Like You... (2001)
★ 6/10
Jane Goodale has everything going for her. She's a producer on a popular daytime talk show, and is in a hot romance with the show's dashing executive producer Ray. But when the relationship goes terribly awry, Jane…