Movies Like Chromosome Plus the Gift of Being Different

If you liked Chromosome Plus the Gift of Being Different (2025), a comedy and music movie directed by Pascale Rocard and Gil Valery, here are 20 movies with a similar feel, based on TMDB's recommendations. Each one links to its cast, trailer and where it's streaming.

1
Sneakerella (2022)
★ 5.9/10Also music and comedy
When El, an aspiring sneaker designer from Queens, meets Kira King, the fiercely independent daughter of legendary basketball star and sneaker tycoon Darius King, sparks fly as the two bond over their mutual affinity…
2
Arctic Dogs (2019)
★ 5.9/10Also animation and comedy
Animals band together to save the day when the evil Otto Von Walrus hatches a sinister scheme to accelerate global warming and melt the Arctic Circle.
3
Chicken for Linda! (2023)
★ 6.9/10Also animation and comedy
Single mother Paulette decides to make up for her mistake by cooking a chicken with peppers for her daughter—only she can't cook and shopkeepers are on strike.
4
Yellow Mirror (2026)
★ 8.1/10Also animation and comedy
A defective lamp reveals a heartbreaking truth about what Homer believes is reality, and an AI-powered tablet befriends and controls Maggie. The Simpsons struggle to find the light through two dark tales of the curious…
5
Simpsley (2026)
★ 8.1/10Also animation and comedy
When penniless con-artist Marge Bouvier is sent to Italy to convince wealthy sap Seymour Skinner to come home, she's tempted by the trappings of his affluent lifestyle. But there’s a big fat fly in the ointment…
6
Arlo the Alligator Boy (2021)
★ 6.8/10Also animation and comedy
Upon learning that he is from New York City, a wide-eyed boy, who is half human and half alligator, decides to leave his sheltered life in the swamp and search for his long lost father. A musical adventure.
7
My Little Pony: Equestria Girls - Legend of Everfree (2016)
★ 7.5/10Also animation and music
When Canterlot Highschool goes on a trip to Camp Everfree, they’re surprised to find a magical force is causing strange things to happen around camp. With the help of the Mane 6 and especially Sunset Shimmer, Twilight…
8
Phineas and Ferb the Movie: Candace Against the Universe (2020)
★ 7.2/10Also animation and comedy
Phineas and Ferb travel across the galaxy to rescue their older sister Candace, who has been abducted by aliens and taken to a utopia in a far-off planet, free of her pesky little brothers.
9
Snoopy Presents: Welcome Home, Franklin (2024)
★ 7.7/10Also animation and comedy
Franklin is new to town and hoping to make friends, but his usual tactics don't work on the Peanuts gang. When the Soap Box Derby arrives, he's sure it's a chance to impress new pals and teams up with the only other…
10
My Little Pony: Best Gift Ever (2018)
★ 7.5/10Also animation and comedy
As the ponies prepare for another Hearth's Warming, families come together to celebrate the holiday; Pinkie Pie, Fluttershy, Applejack, Rarity, and Rainbow Dash are ready for the big day, but Princess Twilight Sparkle…
11
Make Mine Music (1946)
★ 5.8/10Also animation and music
In the tradition of Fantasia, Make Mine Music is a glorious collection of musically charged animated shorts featuring such fun-filled favorites as "Peter and the Wolf", narrated by the beloved voice behind Winnie the…
12
UglyDolls (2019)
★ 6.6/10Also animation and music
In the adorably different town of Uglyville, weirdness is celebrated, strangeness is special and beauty is embraced as more than meets the eye. After traveling to the other side of a mountain, Moxy and her UglyDoll…
13
Tom and Jerry & The Wizard of Oz (2011)
★ 6.2/10Also animation and comedy
After a deadly storm, Tom and Jerry find themselves stranded on an unknown island ruled by the evil Wizard of Oz. As they try to find their way back home, they worry for their master Dorothy's safety.
14
Duck Duck Goose (2018)
★ 6.2/10Also animation and comedy
After he’s grounded by an injury, a high-flying bachelor is saddled with two wide-eyed orphans as they come face-to-face with the dangers and beauty of the outside world.
15
Plankton: The Movie (2025)
★ 6.7/10Also comedy and animation
Plankton's tangled love story with his sentient computer wife goes sideways when she takes a stand — and decides to destroy the world without him.
16
Astro Kid (2019)
★ 7.2/10Also animation and comedy
Terra Willy: Unexplored Planet — Upon the destruction of their ship, Willy is separated from his parents. He lands on a wild and unexplored planet and with the help of Buck, a survival robot, he will have to hold until…
17
Sing (2016)
★ 7.1/10Also animation and comedy
A koala named Buster recruits his best friend to help him drum up business for his theater by hosting a singing competition.
18
The Smurfs: The Legend of Smurfy Hollow (2013)
★ 6.9/10Also animation and comedy
When Brainy Smurf is favored to win the annual Smurfberry Hunt for the ninth year in a row, Gutsy Smurf sets out to discover how Brainy wins every year. Gutsy’s investigation takes him into spooky Smurfy Hollow–and…
19
The Willoughbys (2020)
★ 7.1/10Also animation and comedy
When the four Willoughby children are abandoned by their selfish parents, they must learn how to adapt their Old-Fashioned values to the contemporary world in order to create something new: The Modern Family.
20
Lucky Luke: The Ballad of the Daltons (1978)
★ 6.8/10Also animation and comedy
The Dalton brothers are to receive their dead uncle's fortune if they eliminate the judge and jury responsible for his execution. And to accomplish this task, they must enlist the help of Lucky Luke.